Healthcare >> CEO Interviews >> September 29, 2003

Ralph Ellison – Dor Biopharma Inc (dor)

RALPH M. ELLISON is Chief Executive Officer and President of DOR BioPharma Inc. Dr. Ellison was a co-Founder, Director and Chief Executive Officer of PolaRx Biopharmaceuticals, Inc., an oncology focused drug development company that developed Trisenox (arsenic trioxide) for the treatment of cancer. In January 2000, PolaRx was acquired by Cell Therapeutics, Inc., a public biopharmaceutical company based in Seattle, Washington. During his tenure as the Chief Executive Officer of PolaRx, Dr. Ellison was responsible for all aspects of PolaRx's drug development program from IND filing through the end of Phase III testing. He then worked closely with Cell Therapeutics during the preparation and filing of the new drug application for Trisenox' which was ultimately approved by the FDA in 2000 for the treatment of relapsed acute promyelocytic leukemia (APL), a life-threatening cancer of the blood. Trisenox' was developed and approved in three years (as measured by the time from IND filing to NDA approval), making it the fastest oncology product developed and approved by the FDA. Trisenox' is currently in clinical trials to treat more than 10 types of cancer, including multiple myeloma, myelodysplasia and chronic myeloid leukemia. Prior to founding PolaRx, Dr. Ellison started and ran a contract research organization which was a division of RTL, Inc., a pharmaceutical testing facility based in New York. At RTL he spent five years designing, implementing and completing clinical trials for both large and small pharmaceutical companies. Dr. Ellison's experience includes the development of anticancer compounds, antifungals, analgesics, anti-inflammatories, antibiotics and drug delivery systems. Dr. Ellison holds a degree of Doctor of Medicine from the University of the Witwatersrand in South Africa and a Master of Business Administration degree from the University of Cape Town, South Africa. Profile
TWST: Would you give us a brief overview of DOR BioPharma, both the

history and the company as it is today?

Dr. Ellison: Although DOR BioPharma has been around for many years, the

DOR that I