Healthcare >> CEO Interviews >> July 5, 2004

JOHN BONFIGLIO – IMMUNE RESPONSE CORPORATION (IMNR)

JOHN N. BONFIGLIO is Chief Executive Officer of The Immune Response Corporation, a biopharmaceutical company co-founded by medical pioneer Jonas Salk and based in Carlsbad, California. Prior to joining The Immune Response Corporation, Dr. Bonfiglio was Chief Operating Officer and Executive Vice President for Cypress Biosciences, a San Diego-based biotechnology firm, from June 2001. While at Cypress Biosciences, he oversaw the firm's business, clinical, and research and development efforts for its fibromyalgia drug. Prior to his tenure at Cypress Biosciences, Dr. Bonfiglio spent four years at Peregrine Pharmaceuticals, formerly known as Techniclone Corporation, a Tustin, California-based biotechnology firm focused on cancer treatments. From 1999 to 2001, he served as President and Chief Executive Officer, raising capital through a series of licensing agreements and equity financing agreements and created and executed a strategic plan for refocusing the company on clinical trials and licensing. Dr. Bonfiglio was Vice President, Technology and Business Development of the company from 1997 to 1999, and oversaw research and development, clinical and regulatory affairs, interactions with the U.S. Food and Drug Administration and all product-licensing activities. He also has served as a Director for Baxter Healthcare Corporation, based in Irvine, California, as Director of Business Development and Strategic Planning in the Immunotherapy division and later in the Cardiovascular Surgical division from 1994 to 1997. Dr. Bonfiglio began his biotechnology career with positions at Allergan Inc. as a Scientist in 1983, becoming a Project Director in 1987 and Director of Business Planning in 1991 and eventually Director of Strategic Marketing for Allergan's worldwide ocular anti-infective franchise. Profile
TWST: Give us an overview of your company's technology and the products

that you are developing.

Dr. Bonfiglio: We are a company that's dedicated to developing immune-

based therapies for the