Healthcare >> CEO Interviews >> November 6, 2000

Ron James – Ppl Therapeutics Plc (pth.l)

DR RON JAMES is the Managing Director of PPL Therapeutics. Ron James was involved with the formation of PPL in 1986/1987 at which time he was part of the Prudential's venture capital team. In 1989 the opportunity arose for him to move to PPL as its Managing Director, a job in which he says he has never worked so hard nor had so much fun. Since 1989, PPL has grown from a staff of six to over 200 and has sites in Scotland, US and New Zealand. PPL has raised over GBP25 million from venture capital and corporate investors to support this growth, before achieving a full listing on the London Stock Exchange in June 1996, raising a further GBP35 million on a GBP100 million valuation. PPL later raised a further GBP20 million through a Rights Issue. PPL is perhaps best known for its involvement with Dolly the sheep and later the cloning of pigs but its core business is the production of therapeutic proteins using transgenic animals. PPL is working with major pharmaceutical companies to bring these products to the market. Dr James started his working life as an organic chemist with Glaxo and later moved to Wilkinson Sword where he progressed from bench chemist to Manager of the Chemistry Department with a staff of 40. He then moved into a technology transfer role, which included responsibility for the administration of the company's patent portfolio and negotiating licensing deals with multinational companies, and which produced a six-figure royalty income. At about this time he obtained a finance and accounting qualification and after a short period with Initial Plc looking at acquisitions and franchising opportunities, he joined the Prudential's high tech venture capital team with responsibility for health care and biotech investments. During his four years as a venture capitalist, he looked after the technical side of Celltech and made investments in British Biotechnology, Shield Diagnostics and PPL Therapeutics amongst others, and acted as a Director on the boards of six early stage companies. Profile
TWST: Could you give us a brief overview of PPL Therapeutics?

Dr. James: The company was founded in 1987 to exploit technology that

was developed within the Roslin Institute, now I think