Healthcare >> CEO Interviews >> January 27, 2003

Lewis Gruber – Arryx Inc

LEWIS GRUBER is a Founder and Chief Executive Officer of ARRYX, Inc. He was a Founder and CEO of Hyseq, Inc., a publicly-held biotechnology company, from 1994 through 2000. While CEO of Hyseq, he raised over $70 million in a series of offerings, including the largest initial public offering of a biotechnology company in 1997 (underwritten by Lehman Bros., Salomon Smith Barney, and Fahnestock & Co. Inc.). He also negotiated collaborations for Hyseq totaling over $102 million, including a $60 million collaboration with American Cyanamid Company in December 1999. Mr. Gruber is a member of the Advisory Board to the Center for Biotechnology at Northwestern University's Kellogg Graduate School of Management. He also is a member of the Illinois Strategic Plan for the Biotechnology Industry, where he participated as a member of the venture capital team. Mr. Gruber was a patent attorney with the firm of Marshall, O' Toole, Gerstein, Murray & Borun in Chicago, Illinois, before he joined Hyseq. Profile
TWST: Could we begin with a brief historical sketch of ARRYX and

a picture of things as they are now?

Mr. Gruber: ARRYX was formed around technology coming out of the

University of Chicago,