Healthcare >> CEO Interviews >> October 14, 2002

Stuart Peltz – Ptc Therapeutics Inc

STUART PELTZ, is President and Chief Executive Officer of PTC Therapeutics Inc. Dr. Peltz is a leader in the investigation of mRNA turnover and translation and has been involved in developing the first biochemical assays to investigate the regulation of mRNA turnover as well as in demonstrating the strong connection between the processes of translation and mRNA turnover. Dr. Peltz is widely published and serves on National Institutes of Health and American Cancer Society committees. Dr. Peltz is a recognized scientific leader in the area of post- transcriptional control processes and his work was instrumental in identifying and characterizing components of the nonsense-mediated mRNA decay pathway. His laboratory has established the notion that factors that are involved in nonsense-mediated mRNA turnover are also involved in modulating the processes of translation termination and programmed -1 ribosomal frameshifting. Dr. Peltz received his PhD at the McArdle Laboratory for Cancer Research at the University of Wisconsin. Profile
TWST: Could you begin with a brief historical sketch of PTC Therapeutics

and then bring us up to the present time?

Dr. Peltz: PTC stands for Post Transcriptional Control. It was founded

out of