Healthcare >> CEO Interviews >> July 5, 2004

MICHAEL ASTRUE – TRANSKARYOTIC THERAPIES INC (TKTX)

MICHAEL J. ASTRUE is President and Chief Executive Officer of Transkaryotic Therapies, Inc. Mr. Astrue, former TKT Senior Vice President and General Counsel, brings two decades of public and private sector experience in the biotechnology and pharmaceutical industries. He has served as Chairman of the Massachusetts Biotechnology Counsel and, before joining TKT, was Vice President, Secretary and General Counsel for Biogen, Inc. Mr. Astrue was also a partner at the law offices of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, PC, held several positions with the U.S. Department of Health and Human Services, including General Counsel, and served as Associate Counsel to the President, where he advised and represented former Presidents Ronald Reagan and George Bush. He holds a BA from Yale University and a JD from Harvard Law School. Profile
TWST: Please give us a brief introduction to Transkaryotic Therapies,

Inc., and your products.

Mr. Astrue: We're an operational biotech company. We focus in the area

of protein replacement for