Bruce D. Given

DR. BRUCE D. GIVEN joined Encysive Pharmaceuticals Inc. in April 2002 as
President and Chief Executive Officer, and is a member of its Board of
Directors. Prior to joining Encysive Pharmaceuticals, he was with
Johnson & Johnson as President, International Ortho-Clinical
Diagnostics, and from April 1995 to July 1998, he served as Group Vice
President, Head of U.S. Marketing and Sales, Research and Development
for Janssen Pharmaceutical. He has held various executive and senior
management positions at Sandoz Pharma Ltd., Sandoz Research Institute
and Schering-Plough Corporation. Dr. Given currently serves on the M.D.
Anderson Technology Review Committee. Dr. Given obtained his MD degree
with honors from the Pritzker School of Medicine, University of Chicago
and completed his medical training at the University of Chicago and at
Brigham and Women’s Hospital in Boston, and was a Clinical Fellow at
Harvard Medical School. Dr. Given is certified by the American Board of
Internal Medicine and the Subspecialty Board of Endocrinology and
Metabolism. Dr. Given currently serves on the M.D. Anderson Technology
Review Committee.