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Company Interview Excerpt
MICHAEL RODRIGUEZ - ENDOCARE INC (ENDO)
Full article published: 7/11/2006    


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TWST: We'd like to begin with a brief historical sketch of Endocare and a picture of the things you are doing at the present time.
Mr. Rodriguez: We've been a public company since about 1996. We were spun out of a company called Medstone. Medstone was in the business of lithotripsy, basically ablating kidney stones. So in effect, we've been a public company from our very early history and, in our early years, we were basically a product development company looking to find opportunities most advantageous in terms of commercializing our core competencies. In about 1999, we began focusing on prostate cancer as an area for using our ablative technologies, using freezing temperatures to destroy tissue and tumors. We've been in that business ever since, focusing predominantly on prostate cancer, but also in the most recent few years with cancers of the kidney and liver and lung, and also pain treatment for metastatic bone cancer. Ever since, we've experienced strong rates of growth, most recently about 36% growth in total procedures in the US, and we believe that we've gotten to the point now where, at least in the prostate and kidney areas, we are beginning to emerge as a primary care treatment modality for those cancers.

TWST: Would you explain your core ablation technology and what makes it different from competing technologies?
Mr. Rodriguez: Cryoablation is simply using cold temperatures to destroy tissue. Our technology uses an argon-based system with argon stored at very high rates of pressure: about 3,000 pounds per square inch. As argon depressurizes, it has the ability to get very, very cold, very, very quickly, and that's helpful for the prostate because in that area of the body, temperatures of about minus 20 Celsius to minus 40 Celsius cause cellular destruction. In effect, as we utilize the ability for the gas to depressurize and freeze very quickly, it destroys the tissue, but it preserves the protein structure of the tissue. So the tissue remains intact, but the cells in effect are killed. It's both healthy and cancerous cells, but it has a very high efficacy rate for destroying cancer, and the rate at which the cancer stays killed is also very high. It differs in the sense of other ways of treating prostate cancer, in particular, the surgical removal of the prostate. Most of the time, surgical removal is an open procedure where the patient is being opened at the abdomen and the physician goes in and cuts out the prostate itself and cleans up the surrounding nerves and tissue. Another modality that we compete with is called brachytherapy, which is just the surgical implantation of radioactive seeds that, over time, release radiation into the tissue, and that causes cellular destruction. There are other methods of using radiation and other treatments involving nuclear medicine, but we compete predominantly against brachytherapy and radical prostatectomies.

Tickers included in this excerpt: ENDO


For more information call (212) 952 7433. The Wall Street Transcript does not endorse any of the comments made by interviewees, and does not make stock recommendations.

 

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