Company Interview Excerpt GUALBERTO RUANO - GENAISSANCE PHARMACEUTICALS INC (GNSC) Full article published: 7/8/2002     For Subscribers Get this article online now! Order just this article Get Financial Filings and Annual Reports for Companies featured on TWST from EasyReports.net TWST: What is the summary business overview of Genaissance today? Dr. Rua¤o: Genaissance has been creating a marketplace for DNA variation in the design, development and marketing of drugs. The business model is divided among these opportunities. We provide discovery teams in Pharma and Biotech with databases and informatics tools to analyze DNA variations. There is a technology platform component to the business. In the context of development and marketing, we offer them an opportunity to apply our technology to specific drug programs in which the relationship is geared to a very specific application of the technology. Finally, for the marketing teams in pharmaceutical companies, we license validated markers that Genaissance has been able to connect directly to drug response. So these are licenses on markers for drug response and diagnostics that constitutes the third branch of the business model. The markers I'm speaking of are our proprietary HAP_ Markers and they are already allowing us to make pharmaceutical breakthroughs. For example, earlier this year we reported that our markers could differentiate between the clinical responses of drugs in the same chemical class. Thus, we are making possible the mass customization of medicines based on PNA variation. TWST: What's the competitive landscape today? How rapidly has that landscape been changing and evolving? Dr. Rua¤o: The marketplace has undergone a seismic change certainly over the last few quarters. A lot of companies in the area that we used to call competitors are really changing business models or have undergone changes in their management and operations. The fact is that Genaissance has emerged as the leading company and the strongest company in the pharmacogenetic marketplace. We are in a position to really grow this market and expand it and capitalize on it. The demand for the technology and the application is finally breaking in and other companies were not able to capitalize on it the way that we intend to. Tickers included in this excerpt: GNSC Have TWST notes emailed to you free: Email address: For more information call (212) 952 7400. The Wall Street Transcript does not endorse any of the comments made by interviewees, and does not make stock recommendations.

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